-25dB is a lot of Noise Reduction:
-10dB is about the limit before processing artefacts become conspicuous, (e.g when you inhale).
IMO don’t use any more than -10dB noise reduction, if the noise-floor is still too high try couture expander plugin to push it down, (again -10dB is about the limit before it begins to sound weird) .
BTW notching 60Hz, & using a rumble-filter will reduce your noise-floor measurement quite a bit before any noise-reduction is applied …
