Audacity doesn't run at all.

Based on my experiences, the location of your home folder is the likely culprit.

Please see the following thread:

https://forum.audacityteam.org/t/2-2-1-rc2-aborting-crashing-on-mac-os/47517/1

I’m happy to assist further if you aren’t able to resolve your problem after reading through it.

Best,
Lyle