Plugins Won't Stay Enabled

I pulled up the Add/Remove Plugins menu and enabled the plugins that say new, but when I close the menu, they aren’t enabled and when I reopen the menu, they are back to saying new. What do I do about this?

We need more detail to go on.

Start by telling us the version number of Audacity (all three numbers, see the pink panel at the top of the page). Is it 2.1.2 or 2.1.3-alpha and if the latter, what date?

What are the names of the plugins and where did you get them? Are they Nyquist, VST or some other format? If they are VST, please be aware that Audacity does not support VST 3 plugins or 64-bit VST plugins (except through a 32-bit bridge, which would be a separate download). Synth and instrument VST’s (VSTi) are also not supported.