I have noticed that owners of some other audio devices have reported same kind of issues and I have tried all the proposed settings with no help. Playback from Audacity via Konnekt Live gets distorted and all the other applications producing audio in my Mac do not!
Konnekt Live is connected via Firewire port to my Mac.
I am running MacBook Pro:
Processor 2,53 GHz Intel Core 2 Duo
Memory 4 GB 1067 MHz DDR3
Software OS X 10.9.1 (13B42)
I have latest software version of t.c. electronic Konnekt Live:
Firmware version 2.02
Controlpanel & software package versions are ver 2.5.1