Are you reading a theoretical audiobook or a theoretical podcast?
There are some high points.
You can make a USB microphone cheap and inexpensive by leaving out the filtering and processing for the power coming up the USB cable. You can make a computer cheap and inexpensive by leaving out the filtering and processing for the USB power. Put those two together and you can get The Yeti Curse.
http://kozco.com/tech/audacity/clips/USBMicrophoneWhineClip.mp3
It’s rough to eliminate in post production although we produced a custom filter for it. The filter, unfortunately, deletes some musical tones from your show. The only sure cure is change the microphone or the computer.
USB microphones have other problems as well. They come almost universally with soft volume. These microphones are designed for casual users. If the performer is too loud, distortion can kill the performance permanently. Full Stop. But if they’re too soft, the show can be boosted in Audacity and many times used. So, no contest, right? They all come out of the tin too quiet and usually there isn’t anything you can do about it.
USB Interfaces (I use the Behringer UM2) usually do OK, but there, too, soft volume can be a problem. Most times I use the interface adjusted all the way up. If your interface has the ability to use condenser microphones, then chances are terrific it has 48 volt phantom power and it has the filtering and processing not to have The Yeti Curse.
Mine is on the left.

The other thing good about interfaces is the ability to separate the noisy computer from you. The limit for a USB microphone is about six feet (2M). The limit for an XLR cable can be 100 feet or more.
When someone is writing me checks, I use a small analog mixer although a small USB mixer would work. This gives me the ability to adjust the sound perfectly. The only down side I can think of is the need to be there for the whole show.
This was a radio broadcast I shot. The picture is two shoots, so there’s many more wires than there needs to be.

There is another option. One of our posters gave up on all the computer nonsense and is using a Zoom H2n stand-alone recorder. The daddy to that recorder (H2) is on the stand in this recording.
https://www.youtube.com/watch?v=An-PQEAxsF8&start_radio=1&list=RDAn-PQEAxsF8
I have a Zoom H4.

No computer anywhere near, it has headphone monitoring and it’s portable.
Koz