We have what we have in 2.1.1/2.1.2 - is anyone still arguing to change that along these lines.
I think it's fine to have them all enabled except Classic Filters - and I'm happy to disable the ones I don't usually need in order to get a shorter effects menu.
I'm not a user of either of these features - but five years on I'd back Bill's suggestion to remove the karaoke functionality.
I would want us to retain the mixer board though - it looks useful for multi-track work (IIRC it was a custom piece of work that Vaughan undertook for a paying client).